Toxic relationship is like cancer, once trapped in, it ruins every area of life. Prayers and religious teachings do not prevent one from being victim of toxic relationship, but application of four components of agreement to decision on choice of partners. Understanding these components—emotional compatibility, shared values, mutual respect, and effective communication—is pivotal in building and sustaining relationships that nurture personal growth, emotional well-being, and mutual fulfillment. By prioritizing these aspects, individuals can cultivate relationships founded on trust, empathy, and resilience, creating a supportive and nurturing environment conducive to lasting happiness and well-being.